Affiliation:
1. Department of Immunology, The Weizmann Institute of Science76100 Rehovot, Israel
2. Department of Applied Mathematics and Computer Science, The Weizmann Institute of Science76100 Rehovot, Israel
Abstract
Complex living systems are difficult to understand. They obey the laws of physics and chemistry, but these basic laws do not explain their behaviour; each component part of a complex system participates in many different interactions and these interactions generate unforeseeable, emergent properties. For example, microscopic interactions between non-living molecules, at the macroscopic level, produce a living cell. Here we discuss how to explain such complexity in the format of a dynamic model that is mathematically precise, yet understandable. Precise, computer-aided modelling will make it easier to formulate novel experiments and attain understanding and control of key biological processes.
Subject
Biomedical Engineering,Biochemistry,Biomaterials,Bioengineering,Biophysics,Biotechnology
Cited by
99 articles.
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