Affiliation:
1. Graduate School of Environmental Sciences, Hokkaido University, Sapporo 060-0819, Japan
2. Institute of Low Temperature Science, Hokkaido University, Sapporo 060-0819, Japan
3. Inamori Research Institute for Science, Kyoto 600-8411, Japan
Abstract
Mammalian hibernation is a survival strategy characterized by metabolic suppression and drastically lowering body temperature (Tb), used during harsh seasons with food shortages and cold. The Syrian hamster commences hibernation in response to a short photoperiod and cold but spontaneously concludes hibernation after several months without environmental cues. Little is known about the changes in diel rhythms during hibernation. Using long-term and high-resolution Tb data, we analysed the diel Tb rhythm time-course changes in Syrian hamsters raised under summer-like conditions (long photoperiod (LP) and warm; LP-warm) and transferred to winter-like conditions (short photoperiod (SP) and cold; SP-cold). The diel Tb rhythm was undetectable during the hibernation period (HIBP), reappearing after the HIBP. The phase of this returning rhythm reverted to the LP entrainment phase characteristics despite the ambient SP and then re-entrained to the ambient SP as if the hamsters were transferred from the LP-warm to SP-cold conditions. The diel Tb rhythm reverted from the SP- to LP-type in a hibernation-dependent manner. Under constant dark and cold conditions, the circadian Tb rhythm recovered without photic stimuli following the HIBP. These findings suggest that hibernation involves a program that anticipates the ambient photoperiod when animals emerge from hibernation.
Funder
Japan Agency for Medical Research and Development
Joint Research of the ExCELLS
KAKENHI from Ministry of Education, Culture, Sports, Science, and Technology (MEXT)/Japan Society for the Promotion of Science
Inamori Research Institute for Science
Toray Science Foundation
JST SPRING
Takeda Science Foundation
Subject
General Agricultural and Biological Sciences,General Environmental Science,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
2 articles.
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