Abstract
The paper deals with the chemical and biological properties of substances related to stilboestrol and hexoestrol. The most active substance found is 4:4'-dihydroxy-
γ
:
δ
-diphenyl hexane. It has been shown to be the
meso
or internally compensated form. Next in activity is stilboestrol— 4:4'-dihydroxy-
α:β
-diethylstilbene. The activity of other compounds with varying alkyl constituents on the
αβ
carbon atoms is lower than the activity of the above compounds. Any alteration of the position of the phenolic hydroxyl groups from the 4:4'-position is attended by a marked reduction in activity.
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