The role of the microbiome in host evolution

Author:

Kolodny Oren1ORCID,Callahan Benjamin J.2ORCID,Douglas Angela E.3ORCID

Affiliation:

1. Department of Ecology, Evolution, and Behavior, The Hebrew University of Jerusalem, Giv'at Ram, Jerusalem, Israel

2. Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA

3. Department of Entomology and Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, USA

Abstract

In the last decade, we have witnessed a major paradigm shift in the life sciences: the recognition that the microbiome, i.e. the set of microorganisms associated with healthy animals (including humans) and plants, plays a crucial role in the sustained health and fitness of its host. Enabled by rapid advances in sequencing technologies and analytical methods, substantial advances have been achieved in both identifying the microbial taxa and understanding the relationship between microbiome composition and host phenotype. These breakthroughs are leading to novel strategies for improved human and animal health, enhanced crop yield and nutritional quality, and the control of various pests and disease agents. This article is part of the theme issue ‘The role of the microbiome in host evolution'.

Funder

Gordon and Betty Moore Foundation

Publisher

The Royal Society

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

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