Innate immunity in stem cell-derived hepatocytes
Author:
Affiliation:
1. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin 2, Republic of Ireland
2. MRC Centre for Regenerative Medicine, University of Edinburgh, 5 Little France Drive, Edinburgh EH16 4UU, UK
Abstract
Funder
Chief Scientist's Office
SFI Investigator Award
Publisher
The Royal Society
Subject
General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology
Link
https://royalsocietypublishing.org/doi/pdf/10.1098/rstb.2017.0220
Reference47 articles.
1. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2. Embryonic Stem Cell Lines Derived from Human Blastocysts
3. Modulating Innate Immunity Improves Hepatitis C Virus Infection and Replication in Stem Cell-Derived Hepatocytes
4. Productive Hepatitis C Virus Infection of Stem Cell-Derived Hepatocytes Reveals a Critical Transition to Viral Permissiveness during Differentiation
5. Distinct Antiviral Responses in Pluripotent versus Differentiated Cells
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1. Human PSC-Derived Hepatocytes Express Low Levels of Viral Pathogen Recognition Receptors, but Are Capable of Mounting an Effective Innate Immune Response;International Journal of Molecular Sciences;2020-05-28
2. Integrating natural history collections and comparative genomics to study the genetic architecture of convergent evolution;Philosophical Transactions of the Royal Society B: Biological Sciences;2019-06-03
3. Designer human tissue: coming to a lab near you;Philosophical Transactions of the Royal Society B: Biological Sciences;2018-05-21
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