Grand challenges in space synthetic biology

Author:

Menezes Amor A.1ORCID,Montague Michael G.2,Cumbers John3,Hogan John A.4,Arkin Adam P.156ORCID

Affiliation:

1. California Institute for Quantitative Biosciences, University of California, 2151 Berkeley Way, Berkeley, CA 94704-5230, USA

2. Applications of Vital Knowledge, 113 Chestnut Hill Way, Frederick, MD 21702, USA

3. NASA Ames Space Portal, NASA Ames Research Center, MS 555-2, Moffett Field, CA 94035, USA

4. Bioengineering Branch, NASA Ames Research Center, MS 239-15, Moffett Field, CA 94035, USA

5. E.O. Lawrence Berkeley National Laboratory, 1 Cyclotron Road, MS955-512 L, Berkeley, CA 94720, USA

6. Department of Bioengineering, University of California, Berkeley, CA 94720, USA

Abstract

Space synthetic biology is a branch of biotechnology dedicated to engineering biological systems for space exploration, industry and science. There is significant public and private interest in designing robust and reliable organisms that can assist on long-duration astronaut missions. Recent work has also demonstrated that such synthetic biology is a feasible payload minimization and life support approach as well. This article identifies the challenges and opportunities that lie ahead in the field of space synthetic biology, while highlighting relevant progress. It also outlines anticipated broader benefits from this field, because space engineering advances will drive technological innovation on Earth.

Publisher

The Royal Society

Subject

Biomedical Engineering,Biochemistry,Biomaterials,Bioengineering,Biophysics,Biotechnology

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