Who are you, subdistal appendages of centriole?

Author:

Uzbekov Rustem12ORCID,Alieva Irina3

Affiliation:

1. Faculté de Médecine, Université de Tours, 10 Boulevard Tonnellé, 37032 Tours, France

2. Faculty of Bioengineering and Bioinformatics, Moscow State University, Leninskye gory 73, 119234 Moscow, Russia

3. Belozersky Institute of Physico-Chemical Biology, Moscow State University, Leninskye gory 1-40, 119992 Moscow, Russia

Abstract

This review summarizes data that assign morphological, biochemical and functional characteristics of two types of structures that are associated with centrioles: distal appendages and subdistal appendages. The description of centriole subdistal appendages is often a matter of confusion, both due to the numerous names used to describe these structures and because of their variability among species and cell types. Thus, we have summarized our current knowledge in this review. We conclude that distal appendages and subdistal appendages are fundamentally different in composition and function in the cell. While in centrioles there are always nine distal appendages, the number of subdistal appendages can vary depending on the type of cells and their functional state.

Publisher

The Royal Society

Subject

General Biochemistry, Genetics and Molecular Biology,Immunology,General Neuroscience

Reference71 articles.

1. Stubblefield E. 1968 Centriole replication in a mammalian cell. In The proliferation and spread of neoplastic cells (ed. MD Anderson) pp. 175–193. Baltimore MD: Williams and Wilkins Co.

2. Centrosome composition and microtubule anchoring mechanisms

3. Uzbekov RE Alieva IB. 2013 Centrosome: history of investigations and new discoveries; from cytoplasmic granule to the centre of intracellular regulation . Nadezhdina ES (ed). Moscow Russia: Moscow University Press.

4. Pericentriolar material structure and dynamics

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