Carbonate hydroxyapatite functionalization: a comparative study towards (bio)molecules fixation-Reference-Cited by-同舟云学术

Carbonate hydroxyapatite functionalization: a comparative study towards (bio)molecules fixation

Published:2014-02-06 Issue:1 Volume:4 Page:20130040
ISSN:2042-8898
Container-title:Interface Focus
language:en
Short-container-title:Interface Focus.

Author:

Russo Laura¹,Taraballi Francesca¹,Lupo Cristina¹,Poveda Ana²,Jiménez-Barbero Jesús¹³,Sandri Monica⁴,Tampieri Anna⁴,Nicotra Francesco¹,Cipolla Laura¹

Affiliation:

1. Department of Biotechnology and Biosciences, University of Milano-Bicocca, Piazza della Scienza 2, Milano 20126, Italy

2. Servicio Interdepartamental de Investigación, University Autonoma of Madrid, Madrid 28049, Spain

3. Department of Chemical and Phisical Biology, Centro de Invesigaciones Biológicas, CSIC, Ramiro de Maeztu 9, Madrid 28040, Spain

4. Institute of Science and Technology for Ceramics – National Research Council of Italy (ISTEC-CNR), Via Granarolo, 64, Faenza, Ravenna 48018, Italy

Abstract

Different methods for the functionalization of carbonate hydroxyapatite granules with free amine groups by reaction with (3-aminopropyl)triethoxysilane (APTES) have been compared in order to improve the potential for tethering of bioactive molecules to bioceramics. The combined use of tetraethoxyorthosilicate and APTES with acid catalysis resulted in an evident increase in amine surface grafting.

Publisher

The Royal Society

Subject

Biomedical Engineering,Biomaterials,Biochemistry,Bioengineering,Biophysics,Biotechnology

Link

https://royalsocietypublishing.org/doi/pdf/10.1098/rsfs.2013.0040

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