Stem cell myths

Author:

Magnus Tim1,Liu Ying1,Parker Graham C2,Rao Mahendra S13

Affiliation:

1. Stem Cell Section, Laboratory of Neurosciences, National Institute on Aging, NIH333 Cassell Drive, Room 406A, Baltimore, MD 21224, USA

2. Children's Research Center of Michigan, The Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Children's Hospital of MichiganDetroit, MI 48201, USA

3. Corporate Research Laboratories, Invitrogen Corporation1620 Faraday Avenue, Carlsbad, CA 92008, USA

Abstract

Stem cells, although difficult to define, hold great promise as tools for understanding development and as therapeutic agents. However, as with any new field, uncritical enthusiasm can outstrip reality. In this review, we have listed nine common myths that we believe affect our approach to evaluating stem cells for therapy. We suggest that careful consideration needs to be given to each of these issues when evaluating a particular cell for its use in therapy. Data need to be collected and reported for failed as well as successful experiments and a rigorous scientific approach taken to evaluate the undeniable promise of stem cell biology.

Publisher

The Royal Society

Subject

General Agricultural and Biological Sciences,General Biochemistry, Genetics and Molecular Biology

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