Tumour neoantigen heterogeneity thresholds provide a time window for combination immunotherapy
Author:
Affiliation:
1. ICREA-Complex Systems Lab, Universitat Pompeu Fabra, 08003 Barcelona, Spain
2. Institut de Biologia Evolutiva (CSIC-UPF), Psg Maritim Barceloneta, 37, 08003 Barcelona, Spain
3. Santa Fe Institute, 399 Hyde Park Road, Santa Fe NM 87501, USA
Abstract
Funder
Ministerio de Economía y Competitividad
Fundación Banco Santander
Agència de Gestió d'Ajuts Universitaris i de Recerca
Santa Fe Institute
Departament d'Innovació, Universitats i Empresa, Generalitat de Catalunya
Publisher
The Royal Society
Subject
Biomedical Engineering,Biochemistry,Biomaterials,Bioengineering,Biophysics,Biotechnology
Link
https://royalsocietypublishing.org/doi/pdf/10.1098/rsif.2020.0736
Reference52 articles.
1. Clonal evolution in cancer
2. Genomic instability — an evolving hallmark of cancer
3. Cancer drug resistance: an evolving paradigm
4. Tumour heterogeneity and the evolution of polyclonal drug resistance
5. Adaptive Immune Resistance: How Cancer Protects from Immune Attack
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