Influence of transmural repolarization gradients on the electrophysiology and pharmacology of ventricular myocardium. Cellular basis for the Brugada and long–QT syndromes

Author:

Antzelevitch C.1,Nesterenko V. V.1,Muzikant A. L.2,Rice J. J.2,Chen G.2,Colatsky T.2

Affiliation:

1. Masonic Medical Research Laboratory, 2150 Bleecker Street, Utica, NY 13501, USA ()

2. Physiome Sciences, 307 College Road, East Princeton, NJ 08540–6608, USA

Publisher

The Royal Society

Subject

General Physics and Astronomy,General Engineering,General Mathematics

Reference58 articles.

1. Antzelevitch C. & Dumaine R. 2001 Electrical heterogeneity in the heart: physiological pharmacological and clinical implications. In Handbook of physiology. The heart (ed. A. A. Fozzard & J. J. Solaro). New York: Oxford University Press. (In the press.)

2. Clinical relevance of cardiac arrhythmias generated by afterdepolarizations

3. Heterogeneity within the ventricular wall. Electrophysiology and pharmacology of epicardial, endocardial, and M cells.

4. Antzelevitch C. Sicouri S. Lukas A. Nesterenko V. V. Liu W. W. & Di Diego M. M. 1995 Regional differences in the electrophysiology of ventricular cells: physiological and clinical implications. In Cardiac electrophysiology. From cell to bedside (ed. P. P. Zipes & J. Jalife) pp. 228-245. Philadelphia PA: Saunders.

5. Cellular and Ionic Mechanisms Underlying Erythromycin-Induced Long QT Intervals and Torsade de Pointes

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