The synthesis of a substance allied to adrenalin

Abstract

The isolation of adrenalin from the suprarenal gland by Takamine (1) and by Aldrich (2) in 1901 has led to a considerable amount of work on the chemical nature of this remarkable substance. It is, however, only within the last two years that satisfactory elementary analyses and molecular weight determinations have been made, and the exact structural formula is still unsettled. Two formulæ have been proposed, either of which will account for most of the observed facts concerning the chemical behaviour of adrenalin, although there are other possible structures which may demand consideration.