Abstract
Studies of mosaics (Sturtevant 1932) and transplantation experiments (Ephrussi and Beadle 1935) have shown that the development of vermilion eye colour in
Drosophila melanogaster
is not always autonomous, that is, genetically vermilion (
v
) eye tissue may appear phenotypically wild type in the presence of not-vermilion tissue in other parts of the body. A specific diffusible substance, “
v
+
substance”, has been assumed to be responsible for this change in the pigmentation of vermilion eye tissue (Beadle and Ephrussi 1936). It is the purpose of this paper to present data bearing on two questions: 1. When in development is
v
+
substance produced? 2. At what stages of development can the addition of
v
+
substance produce an effect? A preliminary discussion of experiments bearing on these questions has been published elsewhere (Ephrussi, Clancy, and Beadle 1936).
Reference4 articles.
1. Beadle G. W. and Ephrussi B. 1936 Genetics 21 225.
2. Ephrussi B. and Beadle G. W. 1935 C .R . A cad. P aris 201 98.
3. C .R;Ephrussi B .;Acad. Paris,1936
4. Proc. V Ith In t;Sturtevant A. H .;Conf. Genet.,1932
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