Selective population shifts in mixtures of d-arabinose positive and d-arabinose negative strains of coliform bacteria

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Abstract

Normal strains of Bacterium lactis aerogenes and of Escherichia coli only utilize d-arabinose after a long lag (A - ), but can become adapted to use it freely (A + ). In a medium not containing d-arabinose the A + and A - types can compete for predominance as more or less independent strains. The result of the competition in the examples studied never depended upon the initial proportions of the two types (as certain selective mechanisms would suggest) but simply upon the relative extent to which each strain had been previously acclimatized to the specific minimal medium used for the competitive growth. According to the previous history either type could be initially selected, or an even balance preserved for a considerable time. Superposed on the selection of the A + or of the A - cells there was a certain tendency for the A + cells to lose their adaptation to d-arabinose. It was very slight with Bact. lactis aerogenes and much more marked with E. coli .

Publisher

The Royal Society

Subject

General Medicine

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Cyril Norman Hinshelwood, 1897-1967;Biographical Memoirs of Fellows of the Royal Society;1973-12

2. The stability of an adaptive enzyme formed during growth of Bact. lactis aerogenes (Aerobacter aerogenes) in D-arabinose I. Complex history of the adaptive changes;Proceedings of the Royal Society of London. Series B. Biological Sciences;1962-01-09

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