A general theory of the distribution of gene frequencies - I. Overlapping generations

Abstract

The distribution of gene frequency at a single locus in a population of diploid individuals, with two sexes, subject to mutation, non-random mating and phenotypic selection, is obtained in the case where the generations are overlapping so that individuals die one by one. This distribution is of the same form as that obtained by heuristic methods by S. Wright in a randomly mating population but the coefficients are altered both by the non-randomness of the mating and the overlapping of the generations.