The HEV Ventilator: at the interface between particle physics and biomedical engineering-Reference-Cited by-同舟云学术

The HEV Ventilator: at the interface between particle physics and biomedical engineering

Published:2022-03 Issue:3 Volume:9 Page:
ISSN:2054-5703
Container-title:Royal Society Open Science
language:en
Short-container-title:R. Soc. open sci.

Author:

Buytaert Jan¹^ORCID,Collins Paula¹²^ORCID,Abed Abud Adam¹²^ORCID,Allport Phil³^ORCID,Pazos Álvarez Antonio⁴^ORCID,Akiba Kazuyoshi⁵^ORCID,de Aguiar Francisco Oscar Augusto¹⁶^ORCID,Bay Aurelio⁷^ORCID,Bernard Florian⁷,Baron Sophie¹^ORCID,Bertella Claudia¹^ORCID,Brunner Josef X.⁸^ORCID,Bowcock Themis²^ORCID,Buytaert-De Jode Martine¹,Byczynski Wiktor¹⁹,De Carvalho Ricardo¹⁰,Coco Victor¹^ORCID,Collins Ruth¹¹^ORCID,Dikic Nikola¹²^ORCID,Dousse Nicolas¹⁰,Dowd Bruce¹³,Dreimanis Kārlis¹⁴^ORCID,Dumps Raphael¹,Durante Paolo¹,Fadel Walid¹,Farry Stephen²^ORCID,Fernàndez Prieto Antonio⁴^ORCID,Fernàndez Tèllez Arturo¹⁵^ORCID,Flynn Gordon¹³¹⁶,Franco Lima Vinicius²,Frei Raymond⁷,Gallas Torreira Abraham⁴^ORCID,García Chàvez Tonatiuh¹⁵^ORCID,Gazis Evangelos¹⁷^ORCID,Guida Roberto¹^ORCID,Hennessy Karol²^ORCID,Henriques Andre¹^ORCID,Hutchcroft David²^ORCID,Ilic Stefan¹²^ORCID,Ivanovs Artūrs¹⁴,Jevtic Aleksandar¹⁸^ORCID,Jimenez Dominguez Emigdio¹⁵^ORCID,Joram Christian¹^ORCID,Kapusniak Kacper¹,Lemos Cid Edgar⁴^ORCID,Lindner Jana¹⁹,Lindner Rolf¹,Ivàn Martínez Hernàndez M.¹⁵,Meboldt Mirko²⁰^ORCID,Milovanovic Marko¹²¹^ORCID,Mico Sylvain¹,Morant Johan¹,Morel Michel¹^ORCID,Männel Georg²²^ORCID,Murray Dónal⁶,Nasteva Irina²³^ORCID,Neufeld Niko¹^ORCID,Neuhold Igor¹^ORCID,Pardo-Sobrino López Francisco²⁴,Pèrez Trigo Eliseo⁴^ORCID,Pichel Jallas Gonzalo⁴,Pilorz Edyta¹,Piquilloud Lise²⁵^ORCID,Pons Xavier¹,Reiner David²⁶^ORCID,Règules Medel Hector David¹⁵^ORCID,Rodríguez Ramírez Saul¹⁵^ORCID,Rodíguez Cahuantzi Mario¹⁵^ORCID,Roosens Carl¹⁸,Rostalski Philipp²⁷²²^ORCID,Sanders Freek¹,Saucet Eric¹⁰,Schmid Daners Marianne²⁰^ORCID,Schmidt Burkhard¹,Schoettker Patrick²⁸^ORCID,Schwemmer Rainer¹,Schindler Heinrich¹,Sharma Archana¹,Sivakumaran Derick²⁰^ORCID,Sigaud Christophe¹^ORCID,Spitas Vasilios¹⁷,Steffen Nicola²⁰,Svihra Peter⁶^ORCID,Tejeda Muñoz Guillermo¹⁵^ORCID,Tachatos Nikolaos²⁰^ORCID,Tsolakis Efstratios¹⁷,van Leemput Jan¹⁸^ORCID,Vignaux Laurence²⁹,Vasey Francois¹^ORCID,Woonton Hamish³⁰³¹,Wyllie Ken¹

Affiliation:

1. European Organization for Nuclear Research, Espl. des Particules 1, 1211 Meyrin, Geneva, Switzerland

2. Oliver Lodge Laboratory, University of Liverpool, Liverpool L69 7ZE, UK

3. Particle Physics Group, School of Physics and Astronomy, University of Birmingham, Birmingham B15 2TT, UK

4. Instituto Galego de Física de Altas Enerxías (IGFAE), Universidade de Santiago de Compostela, Santiago de Compostela, 15782 Galicia, Spain

5. Nikhef National Institute for Subatomic Physics, Amsterdam 1098 XG, The Netherlands

6. Department of Physics and Astronomy, University of Manchester, Manchester M13 9PL, UK

7. Institute of Physics, Ecole Polytechnique Fédérale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland

8. Neosim AG, CH-7000 Chur, Switzerland

9. Tadeusz Kosciuszko Cracow University of Technology, 31-155 Cracow, Poland

10. Hôpitaux Universitaires de Genève, 1205 Genève, Switzerland

11. Department of Molecular Medicine, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA

12. Applied Physics Laboratory, Faculty of Electronic Engineering, University of Nis˘, Aleksandra Medvedeva 14, Nis˘ 18000, Serbia

13. Prince of Wales Hospital, Randwick, New South Wales 2052, Australia

14. Centre of High-Energy Physics and Accelerator Technologies and Faculty of Computer Science and Information Technology, Riga Technical University, 1 Kalku Street, Riga LV-1658, Latvia

15. Facultad de Ciencias Físico Matemàticas, Benèmerita Universidad Autónoma de Puebla, Apartado Postal 165, 72000 Puebla, Pue., Mèxico

16. University of New South Wales, Sydney, New South Wales 2052, Australia

17. National Technical University of Athens - NTUA, Zografou Campus, 15780 Athens, Greece

18. GZA Hospitals, 2018 Antwerp, Belgium

19. University of Applied Sciences Offenburg, 77652 Offenburg, Baden-Wuerttemberg, Germany

20. Product Development Group Zurich, Department of Mechanical and Process Engineering, ETH Zurich, 8092 Zurich, Switzerland

21. Deutsches Elektronen-Synchrotron (DESY), Platanenallee 6, 15738 Zeuthen, Germany

22. Fraunhofer Research Institution for Individualized and Cell-based Medical Engineering (IMTE), 23562 Lübeck, Germany

23. Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro 21941-972, Brazil

24. Anesthesiology-Reanimation and Pain Therapeutics Service, Lucus Augusti University Hospital, 27003 Lugo, Spain

25. Adult Intensive Care Unit, University Hospital and University of Lausanne, Lausanne, Switzerland

26. John Curtin School of Medical Research, Canberra, Australian Capital Territory 2600, Australia

27. Institute for Electrical Engineering in Medicine, University of Lübeck, 23562 Lübeck, Germany

28. Centre Hospitalier Universitaire Vaudois, Lausanne CH-1011, Switzerland

29. Cardio-Respiratory Units, Hôpital de La Tour, 1217 Meyrin, Switzerland

30. Monash Health, Melbourne, Victoria 3168, Australia

31. Dandenong Hospital, Melbourne, Victoria 3175, Australia

Abstract

A high-quality, low-cost ventilator, dubbed HEV, has been developed by the particle physics community working together with biomedical engineers and physicians around the world. The HEV design is suitable for use both in and out of hospital intensive care units, provides a variety of modes and is capable of supporting spontaneous breathing and supplying oxygen-enriched air. An external air supply can be combined with the unit for use in situations where compressed air is not readily available. HEV supports remote training and post market surveillance via a Web interface and data logging to complement standard touch screen operation, making it suitable for a wide range of geographical deployment. The HEV design places emphasis on the ventilation performance, especially the quality and accuracy of the pressure curves, reactivity of the trigger, measurement of delivered volume and control of oxygen mixing, delivering a global performance which will be applicable to ventilator needs beyond the COVID-19 pandemic. This article describes the conceptual design and presents the prototype units together with a performance evaluation.

Publisher

The Royal Society

Subject

Multidisciplinary

Link

https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.211519

Reference37 articles.

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