Author:
Liang Shanshan,Li Wenjun,Zhang Xinyue,Ma Zhongying,Li Hongxiang,Yuan Fusong
Abstract
Oral sutures are common and in high demand for oral treatments, and invariably increase physicians' workload. Herein, we examined the degradation of magnesium alloy pins with different elemental compositions and processing technologies both in vivo and in vitro, and analyzed
their cytocompatibilities to verify the feasibility of their use as oral tissue suture materials. The results showed that Mg–Zn–Ca–4Ag, which completely degraded in less than a week in vitro, exhibited large areas of corrosion, local fractures within two weeks, and
degraded almost completely within a period of four weeks in vivo. The other magnesium alloy pins studied herein showed no distinct degradation even after two months, with small amounts of pitting corrosions found on the surface. The cytocompatibility test revealed that Mg–Zn–Ca–4Ag
showed good biocompatibility and promoted cell growth when the Mg concentration was 50 g/mL. Therefore, Mg–Zn–Ca–4Ag can be biocompatible, while degrading within a month. Therefore, by further optimizing the processing technology and composition, magnesium alloys are expected
to emerge as new materials for oral sutures. Moreover, staplers are expected to emerge as a new method for oral, soft-tissue suturing.
Publisher
American Scientific Publishers
Subject
General Materials Science
Cited by
2 articles.
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