Biological Applications, Green Synthesis, Characterization of Silver Nanoparticles (AgNPs) Using Artemisia annua L.-Reference-Cited by-同舟云学术

Biological Applications, Green Synthesis, Characterization of Silver Nanoparticles (AgNPs) Using Artemisia annua L.

Published:2021-07-01 Issue:7 Volume:13 Page:1304-1309
ISSN:1947-2935
Container-title:Science of Advanced Materials
language:en
Short-container-title:sci adv mater

Author:

Ghramh Hamed A.¹,Al-Qthanin Rahmah N.²,Ahmad Zubair¹,Ibrahim Essam H.¹,Kilany Mona¹,Khan Khalid Ali¹,Al-Solami Habeeb Mansour A.³,Khalofah Ahlam¹,Alahmari Abeer¹,Khan Farhat S.⁴,Alamri Ahmad M.⁵,Asiri Asma N.²,Asiri Fawziah M.⁶

Affiliation:

1. Research Center for Advanced Materials Science (RCAMS), King Khalid University, Abha 61413, Saudi Arabia

2. Biology Department, Faculty of Science, King Khalid University, Abha 61413, Saudi Arabia

3. Department of Biological Sciences, Faculty of Science, King Abdulaziz University, Jeddah, 21589, Saudi Arabia

4. Biology Department, College of Arts and Sciences, Dehran Junub, King Khalid University, Abha 61413, Saudi Arabia

5. Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, 61421, Saudi Arabia

6. Department of Biology, Faculty of Science, University of Bisha, Bisha 61922, Saudi Arabia

Abstract

ABSTRACTThis article reports on the silver nanoparticles (AaAgNPs) that were green-synthesized by using Artemisia annua L. extract (AaExt) and their collective biological applications. Active biomolecules in the extract and extract containing AgNPs were characterized using Fourier-transform-infrared-spectroscopy (FTIR) and AgNPs were monitored by UV/vis spectroscopy and SEM (scanning electron microscopy) analysis. The size of the particle is around 100 nm. The antibacterial activity was measured by the disk diffusion method against the Gram-negative/positive pathogenic bacteria. The extract and extract containing AgNPs showed a significant antibacterial activity. Cytotoxic potential of the synthesized AgNPs was analyzed against the rat splenocytes. The results showed that there were cytotoxic effects of A. annua leaves extract but stimulatory effects when the extract contained AgNPs on normal splenocytes. Extract of A. annua showed very little increase in liver enzymes. Regarding the larvicidal activity, the extract containing AgNPs was more effective than the crude leaves extract against 4th instar larvae of Culex pipiens (LC50 = 171.378 ppm) compared to the plant extract (LC50 = 5389.726 ppm) by about 31.449 folds.

Publisher

American Scientific Publishers

Subject

General Materials Science