Clinical Study of Correlation Between Osteoporosis and Osteoarthritis of Knee Joint Using Gold Nanomaterial Contrast Agent

Abstract

The relationship between osteoporosis (OP) and knee osteoarthritis (OA) was studied using gold nanomaterial (GNP) contrast agent from the imaging and clinical perspectives. Patients were divided into the OA and OP comorbidity group (experimental), OA group (positive control), and OP group (negative control) and evaluated using the Lysholm knee joint score and traditional Chinese medicine syndrome score. Bone density was measured by parallel X-ray examination, magnetic resonance imaging examination, Recht classification, and arthroscopic Outerbridge classification. GNP contrast agents were used in the medical imaging tests. There were significant differences between the various factors compared between the experimental and positive control groups (P < 0.05). The correlation analysis of the variables and bone mineral density in all patients showed a positive linear relationship (P < 0.05). There was a positive correlation between OP and knee OA. GNP has good clinical value in medical imaging.