Applications of Ultrasound Targeted Micro/Nano Probes and Intelligent Ultrasound Molecular Imaging Technology

Abstract

Targeted ultrasound molecular probes are the core technology of ultrasound molecular imaging, which connect molecular specific antibodies or ligands of the target tissue to the surface of ultrasound contrast agents, enabling ultrasound microbubbles to actively bind to the target tissue, thereby observing the specific imaging of the target tissue at the cellular or molecular level, reflecting the changes in the diseased tissue at the cellular or molecular level. Ultrasound molecular imaging has rapidly developed and applied in the diagnosis and treatment of breast, thyroid, cardiovascular and other diseases, as well as targeted drug delivery and targeted physical therapy of tumors. This article focuses on the theoretical innovation and technological progress of ultrasound micro/nano targeted probes, key technologies of ultrasound molecular imaging, new ultrasound imaging technologies, and the application of ultrasound micro/nano target bubbles in recent years. The integration of multifunctional micro/nano bubbles and multimodal molecular imaging, as well as diagnosis and treatment, is the development trend of ultrasound molecular probes. Artificial intelligence technology will serve as a basic tool to provide technical support for intelligent ultrasound molecular probes and molecular imaging.