Highly Sensitive Enzyme-Less Glucose Biosensor Based on α-Fe2O3 Nanoparticles

Abstract

This paper reports the synthesis, characterization and fabrication of enzyme-less glucose sensor based on iron oxide (α-Fe2O3) nanoparticles synthesized by facile hydrothermal process. The synthesized nanoparticles were characterized by various techniques to understand the morphologies, composition and scattering properties. The morphological and structural studies confirmed the successful formation of α-Fe2O3 nanoparticles in large quantity which exhibiting well-crystallinity and rhombohedral crystal structures. The fabricated enzyme-less glucose sensor based on α-Fe2O3 nanoparticles revealed high sensitivity of 30.89 μA/mM cm2 with a fast response time (5 sec). The fabricated glucose sensor exhibited high reproducibility and its electrochemical response found to be linear over a wide concentration range of glucose from 1 to 10 mM with coefficient of regression (R) = 0.9981.