Research on Radial Basis Function Neural Network Based on Improved Hierarchical Genetic Algorithm in Early Diagnosis of Alzheimer’s Disease

Author:

Han Peiyin1,Ma Jie1,Fang Fang1,Barbara Sevlever2

Affiliation:

1. Department of Geriatrics, Nanjing Drum Tower Hospital, Nanjing, 210000, China

2. Department of Pathology, University Miami, Coral Gables, 33124, USA

Abstract

With the increasing aging level of China’s population, the probability of suffering from Alzheimer’s disease also increases. Genetic Algorithm-Back-Propagation (GA-BP) were introduced and compared, and the effectiveness of Genetic Algorithm-Radial Basis Function (GA-RBF) algorithm in diagnosis and prediction of Alzheimer’s disease was verified by simulation experiments. The results showed that GA-RBF modeling time increased by about 75%, It showed that GA-RBF algorithm can be used helpful to accurately predict the cognitive status of the elderly.

Publisher

American Scientific Publishers

Subject

Health Informatics,Radiology, Nuclear Medicine and imaging

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