Dynamic Analysis of Myocardial Enzymes and Electrocardiogram in Pediatric Pneumonia

Abstract

Objective: The condition of pediatric pneumonia changes rapidly. Non-invasive myocardial enzymes and electrocardiogram (ECG) can reflect the myocardial damage of patients noninvasively. The purpose of this study was to investigate the dynamic changes of myocardial enzymes and ECG in the pediatric pneumonia. Method: A total of 18 pediatric pneumonia cases in our hospital from April 2018 to February 2019 were chosen. Another 18 healthy children were chosen as control group. The activity of creatine kinase (CK), creatine kinase isoenzymes (CK-MB), lactate dehydrogenase (LDH), and Glutamic oxaloacetic transaminase (GOT) was collected, and the ECG were recorded in all subjects. Result: Before treatment, the CK, CK-MB, LDH and GOT in pneumonia group was higher than the data in control group. After treatment, the level decreased significantly, but still slight higher than the data in control group. Compare with control groups, the incidence of abnormal ECG increased significantly. There was no statistical difference of incidence between control group and the patients after treatment. Conclusion: The serum myocardial enzymes such as CK, CK-MB, LDH and GOT and ECG changes are useful markers for monitoring the myocardial injury in pediatric pneumonia.