Assessment of Antimicrobial Features of Selenium Nanoparticles (SeNPs) Using Cyclic Voltammetric Strategy

Author:

Saeed Madiha1,Ansari M. Tayyab2,Kaleem Imdad3,Bajwa Sadia Zafar1,Rehman Asma1,Bano Khizra1,Tehseen Bushra1,Jamil Nuzhat1,Zahoor Mehvish1,Shaheen Ayesha1,Taj Ayesha1,Younis M. Rizwan4,Khan Waheed S.1

Affiliation:

1. Nanobiotechnology Group, National Institute for Biotechnology and Genetic Engineering (NIBGE), Jhang Road Faisalabad-38000, Pakistan

2. Faculty of Pharmacy, University of Lahore (New Campus), Lahore-55150, Pakistan

3. Department of Biosciences, COMSATS Institute of Information Technology (CIIT), Islamabad-45550, Pakistan

4. State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210093, P. R. China

Abstract

The emerging biomedical applications of selenium nanoparticles (SeNPs) require facile and efficient strategy to assess its interactions with cell membrane. In this study, an efficient and reproducible microwave assisted method was used to synthesize SeNPs with controllable size distributions. The physical properties of the emergent structures, such as morphology, structure, and size were studied. The antimicrobial applications of SeNPs were assessed by electrochemical analyses that entailed the systematic acquisition of cyclic voltammetry data. Our results demonstrate a straightforward method to predict the integrity of bacterial cell membranes following the administration of SeNP treatments.

Publisher

American Scientific Publishers

Subject

Condensed Matter Physics,General Materials Science,Biomedical Engineering,General Chemistry,Bioengineering

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