Colorectal Cancer Lymph Node Detection and Anastomotic Safety of Using Carbon Nano-Tracer Following Minimally Invasive Radical Surgery

Abstract

Objective: The goal of this study is to examine the impact of rectal submucosal injection of nano-carbon suspension injection following neoadjuvant therapy for middle and low rectal cancer on lymph node identification and anastomotic safety. Methods: 45 patients with intermediate-to-low grade rectal cancer admitted to the Ningbo Medical Center Lihuili Hospital between March 2019 and March 2022 had their medical records reviewed retrospectively. Patients in case group were injected with nanocarbon suspension under an anoscope into the rectal submucosa patients in control group were not injected with nanocarbon suspension. The lymph node identification and anastomotic consequences were then compared. Results: There were statistically significant differences between the two groups in the average number of lymph nodes discovered in the observation group and the percentage of patients with more than 12 lymph nodes detected. The percentage of patients with lymph node metastases did not significantly. The rates of complications such leakage, hemorrhage, stenosis, and abscesses around the anastomosis were similar in both groups. Conclusion: Nano carbon lymph node tracking is a safe, simple, and easy-to-operate method for increasing the number of lymph nodes detected in surgical specimens of middle and low rectal cancer after neoadjuvant therapy.