The Effects of Carbon Dots from Hordei Fructus Germinatus Carbonisatus on Glycometabolism and α-Glycosidase Activity

Abstract

Hordei Fructus Germinatus Carbonisatus (HFC), the carbonized malt known as Maiya-tan in China, has been used as an effective natural treatment to improve digestion for a long time. In this research, we separated and distinguished CDs (carbon dots) from HFC, which were prepared using traditional methods. The HFC CDs had a lattice spacing of 0.26 nm and an average size of 4.3 nm, according to morphology investigations, which revealed that they were nearly spherical. The significant elements in the HFC CDs were C, O, and N. These HFC CDs produced several emissive traps between π − π* states because they had functional groups including C–OH, –NH, C=O, and C–H on their surface, according to X-ray photoelectron spectroscopy investigation. Our results indicated that HFC CDs could effectively reduce postprandial blood glucose and inhibit α-glycosidase in vitro, which suggested that HFC CDs may affect aspects of carbohydrate metabolism. This work indicates that HFC CDs may have the potential to play a crucial clinical role in regulating blood sugar.