Bibliometric Analysis on Stem Cell Transplantation Treatment for Premature Ovarian Failure

Abstract

To carry out bibliometric analysis on stem cell transplantations for premature ovarian insufficiency (POI), and quickly grasp the clinical significance and potential of stem cell transplantation in the treatment of POI, the current study used the Web of Science core collection to retrieve relevant literature using keywords “stem cells” and “primary ovarian dysfunction”. VOSviewer was used for network visualization analysis of key words, authors, institutions, and countries. The results showed that, annual publications increased steadily from 2000 to 2023 with some fluctuations. China, Shanghai Jiao Tong University, and “Human Reproduction” are the countries, organizations, and journals with the highest output. The keyword map reflects that fertility preservation and hormone replacement therapy are currently hot topics in the treatment of POI. Mesenchymal stem cells (MSCs) and in vitro activation may have the highest potential to be applied in the future. Based on the current bibliometric analysis, the study on clinical efficacy, prognosis, and mechanism of POI treatment using MSCs and their exosomes is a research hotspot with great potential in this field.