Study on the application of internal fixation material implantation in the rehabilitation of spondylolisthesis in children

Abstract

Spondylolisthesis (SP), particularly lumbar SP in children, is mostly caused by dysplasia. Several clinical studies have revealed that bone cement filled with hollow pedicle screws can achieve great benefits in the treatment of SP. However, most of the existing bone cement materials are based on polymethyl methacrylate (PMMA) and calcium phosphate cement (CPC). However, PMMA has poor biocompatibility, due to which its actual efficacy is greatly reduced. Although CPC has good biocompatibility, it exhibits certain cytotoxicity and high pressure in the bone marrow, resulting in fat droplets in blood vessels, which may cause embolisms. This study aimed to investigate the actual efficacy of a new type of bone nanocement filled with hollow pedicle screw in the treatment of 11 children with lumbar SP and to provide a feasible surgical method for the treatment of lumbar SP with hollow pedicle screw filled with bone nanocement.