In Vitro Bioactivity Study on ZnI2-HAp Nanoparticles
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Published:2020-04-01
Issue:4
Volume:15
Page:523-531
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ISSN:1555-130X
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Container-title:Journal of Nanoelectronics and Optoelectronics
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language:en
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Short-container-title:Journal of Nanoelectronics and Optoelectronics
Author:
Alshahrani Mohammad Y.,Algarni H.,AlShahrani Ibrahim,Yahia I. S.,Zahran H. Y.,Ibrahim Essam H.,Kilany Mona,Sayed M. A.,Yousef El Sayed
Abstract
The manufactured powder of immaculate HAp which is doped with 1.0, 5.0, 10, 20, 30, and 40 in wt.% ZnI2 has been prepared via the sol–gel process. The characterization of samples was achieved by X-ray diffraction (XRD), Fourier Transform Infrared spectroscopy (FT-IR)
and Fourier Transform Raman spectroscopy (FT- Raman). The morphology of the obtained HAp powder was studied through SEM analysis. The investigation proves that all prepared samples have the dimension of a nanoscale. The prepared powders were examined for its anti-growth, stimulatory/cytotoxic
potentials on normal/activated mouse splenocytes in vitro as well as the lytic effects on red blood cells (RBCs). Results showed that different preparations of ZnI2 had anti-growth effects on normal mouse splenocytes. The pure HAp, 1% and 10% ZnI2 showed no effects on
stimulated mouse splenic cells while the other preparations 5%, 20%, 30% and 40% ZnI2 showed inhibitory/cytotoxic effects. All ZnI2 preparations showed safe effects on RBCs.
Publisher
American Scientific Publishers
Subject
Electrical and Electronic Engineering,Electronic, Optical and Magnetic Materials
Cited by
1 articles.
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