Temperature-Responsive Glycosides for Controlled Release of Decanol Towards Sustainable Disinfect Effect

Abstract

Controlling the release of decanol with temperature is a reliable way to improve the utilization of decanol. In this paper, a temperature-controlling release decyl glycoside was synthesized using method of Koenigs-Knorr acetyl glycoside synthesis. Thereafter, the resultant decyl glycoside was characterized in terms of thermogravimetric analysis, differential scanning calorimetry and pyrolysis analysis, respectively. Moreover, both the temperature-responsive responsive in vitro release and disinfection activities were also assessed. Finally, the results showed that the yield of decyl glycoside was 81%, which was higher than that conventional formulation. The decyl glycoside possessed outstanding performance of thermostabilization and controlled release properties with temperature. The release of decanol from decyl glycoside could be well described by mechanism of the case II transport and fickian diffusion. Disinfect effect studies have shown a positive correlation between long-term disinfection decyl glycosides and temperature-induced changes in release rate. Based on these results, decyl glycoside could improve stability and long-term disinfection of decanol by controlling temperature, which could be bound to drug, food, and other industry.