Affiliation:
1. Department of Outpatient, People’s Hospital of Lujiang County, Hefei, 230000, Anhui, PR China
2. Department of Obstetrics, People’s Hospital of Lujiang County, Hefei, 230000, Anhui, PR China
Abstract
This study analyzed the clinical effects of cervical dilation balloon and castor oil meal nursing interventions in term induction of labor. The eighty pregnant women who were scheduled for delivery in our hospital between March 2020 and January 2022 were recruited into an observation
group and a control group using a random number table. The control group received oxytocin for labor induction while the observation group received cervical dilation balloon and castor oil meal nursing interventions for labor induction. In addition to clinical treatment experiments, cell experiments
are performed. BeWo cells were cultured to study the effect of estrogen on cell viability, and the expression of matrix metalloproteinase 2 and 9 (MMP2, MMP9) was detected using Western blotting. The endpoints of this study were to investigate the impact of estrogen changes on term-induced
pregnant women and to compare the cervical dilation balloon and castor oil meal nursing interventions with regards to duration of labor, efficacy of cervical ripening, Bishop score of the cervix, postpartum complications, and other relevant indicators. The viability of BeWo cells did not significantly
differ after treatment with different concentrations of 17β-E2 (-> 0.05). The expression of MMP9 after different levels of treatment did not significantly differ (P >0.05), whereas the expression of MMP2 protein in the 5×10−7 and 5×10−8
M treatment groups was lower than that in the control group (P <0.05). The first stage and total duration of labor were significantly shorter in the observation group than that in the control group (P <0.05). The efficacy of cervical ripening was significantly higher in
the observation group than that in the control group (P <0.05). The Bishop score of the cervix was significantly higher in the observation group after intervention (P <0.05). The incidence of complications in the observation group was significantly lower than that in the
control group (P <0.05). Estrogen levels may affect the invasive function of trophoblast cells, causing abnormal placental function. Castor oil has hormonal effects and contains precursors for prostaglandin synthesis and can induce and strengthen contractions, soften the cervix,
and dilate the cervix. The combined use of cervical dilation balloon and castor oil meal in term induction of labor has clear clinical effects, including the effective shortening of labor duration, favorable cervical ripening, significant improvement in the Bishop score of the cervix, and
reduced incidence of complications. This study suggests its potential for clinical application and wider use.
Publisher
American Scientific Publishers
Subject
Renewable Energy, Sustainability and the Environment,Biomaterials,Bioengineering
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