Exploring the Risk Factors of Thrombosis and Bloodstream Infections in Peripherally Inserted Central Catheter (PICC) Patients

Abstract

Objective: To analyze the risk factors of thrombosis and associated bloodstream infections in patients with a peripherally inserted central catheter (PICC). Method: A total of 711 patients who received a PICC in our hospital between February and December 2018 were enrolled in this study. Clinically relevant data were collected, including general information, medical histories, laboratory examinations, etc. The 711 patients underwent risk assessments for thrombosis and bloodstream infections to statistically analyze the relevant risk factors. Result: Thirty-three of the 711 patients developed thrombosis, which is a proportion of 4.64%. In addition, ten patients developed bloodstream infections at an infection rate of 1.41%. For patients with different catheter indwelling times, the difference in the proportion of bloodstream infections was statistically significant (p < 0.05). Additionally, the analysis results showed that a difference in the vein-puncture site and the fibrinogen content is a direct risk factor for thrombosis. Moreover, PICC catheter indwelling is a risk factor for bloodstream infections. Conclusion: The nursing staff should adopt targeted and predictive graded-care interventions, including drug prevention and stratified care, to reduce catheter-related thrombosis in patients.