Three as-synthesized silver nanowires (Ag NWs) with different size on renal cancer treatment

Abstract

In this paper, three as synthesized silver nanowires (Ag NWs 1–3) have been successfully synthesized via the one-step polyol synthesis at 150 °C for 8 h, which use the NaCl, ZnCl2 and CuCl2 as the inorganic control agents to control the size and length of the Ag NWs. Three Ag NWs sample have been characterized by the scanning electron microscope (SEM) and powder X-ray diffraction (PXRD). The novel Ag NWs application on anti-renal cancer was explored and the specific mechanism was determined simultaneously. The results suggested that Ag NWs inhibited renal cancer by decreasing renal cancer cell proliferation and up-regulating SUCLG1 and PCK2 expression. The Ag NWs showed the potential to be developed as the anti-tumor drug.