Tunable Luminescence Emission and Treatment Activity on Sepsis Acute Lung Injury of a New Cd(II) Complex

Abstract

Under the hydrothermal reaction conditions, a novel coordination compound based on Cd(II) ion as nodes formulated as [Cd(L)0.5(bpp)2]n·2n(H2O) (1 H4L = 3,3′,5,5′-azobenzentetracarboxylic acid, bpp = 1,3-bis(4-pyridyl)propane), was synthesized via the dual ligand strategy. By varying the excitation wavelength, compound 1 exhibited tunable luminescence emission. Furthermore, the application values of the compound on sepsisinduced acute lung injury were studied, and the specific mechanism was discussed. The inflammatory cytokines released from alveolar lavage fluid were detected using an ELISA kit after CP therapy. Real-time RT-PCR was applied to monitor the relative expression of lncRNA NANCI in lung epithelial cells.