The recurrence rate of pleomorphic adenoma in the long-term follow-up according to the clinic of maxillofacial surgery

Abstract

In this study we sought to investigate the patients history database, underwent surgical treatment of removing pleomorphic adenoma amass form parotid gland (PG), also identifi replays of mass in the long-term follow-up period. Material and methods: 391 case histories of patients with benign tumours of the (PG) were analysed in detail. 200 (51,1%) patients had a morphological diagnosis of a pleomorphic adenoma (PA). During postoperative follow-up, 39 (n=39) patients were examined, During the ultrasound (sonography) examination were identify 7 patients with replays of neoplasm of parotid salivary gland (pleomorphic adenoma?), the average age of the patients at the time of the examination was 41.6±13.4 years (men — 42 years old, women — 48.8+11.8 years). The sex ratio of patients were 6 females and 1 male patient, the average time of relapse occurred in the long-term follow-up period was 8.3 years. The morphological study of prevues surgery of 7 patients with relapse of neoplasm of parotid salivary gland (pleomorphic adenoma ?), revealed a predominance of mixoid component in all patients, out of 5 patients with PA, the fibrous capsule had a complete structure, the capsule is partially or completely thinned in 1 patient, and in 1 patient is completely absent. Conclusion: By retrospective analysis of the data of patients who underwent to surgery of parotid gland surdested that the likelihood of tumor recurrence increases with the predominance of the myxold component in the structure of pleomorphic adenoma, especially in those where it is limited to the use of the method of ectracapsular enucleation, performed even in an extended version within the surface part of the parotid gland. In addition, the risk of recurrence increases with morphological signs of complete or partial absence of the fibrous capsule of the PA.