Ventricular arrhythmia and torsade de pointe: Dose limiting toxicities of the MDR-modulator S9788 in a phase I trial

Author:

Stupp R.,Bauer J.,Pagani O.,Gerard B.,Cerny T.,Sessa C.,Bastian G.,Sarkany M.,Schläpfer J.,Giroux B.,Leyvraz S.

Publisher

Elsevier BV

Subject

Oncology,Hematology

Reference43 articles.

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3. Expression of a full-length cDNA for the human ‘MDR1’gene confers resistance to clochicine, doxorubicin, and vinblastine;Ueda;Proc Natl Acad Sci USA,1987

4. Does P-glycoprotein predict response to chemotherapy, and if so, is there a reliable way to detect it?;Dalton;J Natl Cancer Inst,1991

5. Effect of S9788, cyclosporin a and verapamil on intracellular distribution of THP-doxorubicin in multidmg-resistant K562 tumor cells, as studied by laser confocal microspectrofluorometry;Sebille;Anticancer Res,1994

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