Giant nodular basal cell skin cancer-Reference-Cited by-同舟云学术

Giant nodular basal cell skin cancer

Published:2023-05-17 Issue:2 Volume:99 Page:80-86
ISSN:2313-6294
Container-title:Vestnik dermatologii i venerologii
language:
Short-container-title:Vestnik dermatologii i venerologii

Author:

Sedova Tatiana G.^ORCID,Elkin Vladimir D.^ORCID

Abstract

The article presents clinical case report of primary giant nodular basal cell skin cancer in two patients at the age of 64 and 68 years and with disease duration of 20 and 15 years respectively. Psychological status of fear and anxiety are considered the main reasons for the late health encounter. The clinical picture of the case report was characterized by a slow long-term asymptomatic growth of solitary tumor-like mushroom-shaped nodes of stagnant pink color with a bumpy surface, densely elastic consistency, adherent to underlying soft tissues and sized 9.5 7.0 cm and 5.0 9.0 cm respectively. Giant basaliomas were located on the scalp in a woman and on the trunk skin in a man. The clinical tumors features are corresponded to those of a large conglomerated basal cell skin cancer. The article also presents a description of the clinical and dermatoscopic picture of giant nodular basaliomas. The patients underwent curative surgical excision of tumors with pathomorphological examination of the postoperative material. The histological picture of giant basal cell carcinoma in both cases is represented by tumors of a complex structure, namely a solid adenoid type with invasion into the reticular dermis and subcutaneous fat. The low biological potential of giant nodular basaliomas has been established.

Publisher

Rossijskoe Obschestvo Dermatovenerologov i Kosmetologov

Subject

Infectious Diseases,Dermatology

Link

https://vestnikdv.ru/jour/article/viewFile/1407/pdf

Reference17 articles.

1. Елькин В.Д., Митрюковский Л.С., Седова Т.Г. Частная дерматоонкология. Часть 1. Опухоли, опухолеподобные образования и пороки развития эпидермиса и придатков кожи. Пермь: Перм. кн. изд-во, 2017. 744 с. [El'kin VD, Mitrjukovskij LS, Sedova TG. Chastnaja dermatoonkologija (Private dermato-oncology). Part 1. Opuholi, opuholepodobnye obrazovanija i poroki razvitija jepidermisa i pridatkov kozhi. (Tumors, tumor-like formations and malformations of the epidermis and skin appendages.) Perm: Perm Book Publishing House; 2017. 744 p. (In Russ.)] ISBN 978-5-904037-77-2

2. Куклин И.А., Кохан М.М., Волкова Н.В., Скляр М.С., Изюров Л.Н., Сафонова Г.Д. и др. Случай гигантской формы базально-клеточного рака кожи в результате многолетнего течения опухолевого процесса и поздней обращаемости больного. Уральский медицинский журнал. 2015;(7):98–102 [Kuklin IA, Kohan MM, Volkova NV, Skljar MS, Izjurov LN, Safonova GD, et al. A case of a giant form of basal cell skin cancer as a result of a long-term course of the tumor process and late referral of the patient. Ural'skij medicinskij zhurnal. 2015;(7):98–102. (In Russ.)]

3. Писклакова Т.П. Базально-клеточный рак кожи: новые возможности патогенетической терапии. Клиническая дерматология и венерология. 2014;12(6):4–8 [Pisklakova TP. Basal cell carcinoma: new opportunities for pathogenetic therapy. Klinicheskaja dermatologija i venerologija. 2014;12(6):4–8. (In Russ.)]

4. Хлебникова А.Н., Кладова A.Ю., Кириченко И.А., Сарханн B.C. К проблеме гигантских базалиом. Клиническая дерматология и венерология. 2007;5(1):9–12 [Hlebnikova AN, Kladova AYu, Kirichenko IA, Sarhann BC. To the problem of giant basaliomas. Klinicheskaja dermatologija i venerologija. 2007;5(1):9–12. (In Russ.)]

5. Побилат А.Е., Прохоренков В.И., Карачева Ю.В., Батухтин Е.Н. Гигантские базалиомы. Клиническая дерматология и венерология. 2009;7(1):37–40 [Pobilat AE, Prohorenkov VI, Karacheva JuV, Batuhtin EN. Giant basaliomas. Klinicheskaja dermatologija i venerologija. 2009;7(1):37–40. (In Russ.)]