Current approaches to the external therapy of psoriasis

Abstract

Topical glucocorticosteroids rank first among drugs for the external therapy of psoriasis. When selecting a drug, it is necessary to take into account the disease sensitivity to different classes of topical steroids. Dermovate (clobetasol propionate) is the most efficient drug for the external therapy of moderate to severe psoriasis. When this drug was used as a part of the complex treatment of psoriasis, regression of eruptions was observed within three weeks in 97.4% of patients, and in 91.5% of patients if the process was localized in the area of palms and soles. Major indications for its use are torpidity with regard to the previous therapy, localization in the field of palms and soles, and substantial reduction in the life quality.