The prevalence incidence of psoriatic onychodystrophy and the significance of its symptoms for the diagnosis of psoriatic arthritis

Abstract

Background. There is a need to assess the diagnostic significance of the symptoms of nail damage, as well as available effective methods for diagnosing psoriatic arthritis in the early stages. Aims. To study of the occurrence of symptoms of psoriatic onychodystrophy in patients with psoriatic arthritis and assessment of the diagnostic significance of the ultrasound method for diagnosing enthesitis as an early symptom of psoriatic arthritis among patients with onychodystrophy and without psoriatic arthritis in case history. Methods. It was a prospective clinical study based on the Clinic of Skin and Venereal Diseases of the Military Medical Academy. We made the clinical assessment of symptoms of onychodystrophy among patients with and without psoriatic arthritis and the evaluation of the diagnostic significance of the ultrasound method for diagnosing psoriatic arthritis under the control of magnetic resonance imaging of the joints. Results. 45 patients with psoriatic arthritis and 134 patients with psoriasis without arthritis were examined. Psoriatic onychodystrophy was significantly more common in the group of patients with psoriatic arthritis (p = 0.028). The most characteristic symptoms of onychodystrophy in patients with psoriatic arthritis are oil spots and symptom combinations: oil spots and subungual hyperkeratosis, onycholysis and subungual hyperkeratosis, pits and longitudinal ridges, oil spots and longitudinal ridges. The ultrasound method for the diagnosis of psoriatic arthritis has shown its high diagnostic significance (Se = 81.8%, Sp = 88.0%). The most characteristic symptoms of arthritis on ultrasound examination are hypoechoic structures of the Achilles tendons and the presence of fluid in the peri- and retro-Achilles bursa. Conclusions. The symptom of oil spots and combinations of oil spots with subungual hyperkeratosis, onycholysis with subungual hyperkeratosis, pits with longitudinal ridges and oil spots with longitudinal ridges can be considered diagnostically significant in the examination of early psoriatic arthritis, and the ultrasound method is highly effective in diagnosing early manifestations of arthritis.