Federal guidelines on diagnosis and treatment of community-acquired pneumonia

Author:

Avdeev S. N.1ORCID,Dekhnich A. V.2ORCID,Zaytsev A. A.3ORCID,Kozlov R. S.4ORCID,Rachina S. A.5ORCID,Rudnov V. A.6ORCID,Sinopal’nikov A. I.7ORCID,Tyurin I. E.7ORCID,Fesenko O. V.7,Chuchalin A. G.8ORCID

Affiliation:

1. Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia

2. Smolensk State Medical University, Healthcare Ministry of Russia

3. Main Military Clinical Hospital named after academician N.N.Burdenko, Ministry of Defense of the Russian Federation

4. Smolensk State Medical University, Healthcare Ministry of Russia; Interregional Association for Clinical Microbiology and Antimicrobial Chemotherapy

5. Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

6. Federal State Budget Educational Institution of Higher Education “Ural State Medical University” of the Ministry of Health of the Russian Federation; State Autonomous Healthcare Institution of the Sverdlovsk Region “Sverdlovsk Regional Oncological Dispensary”

7. Russian Medical Academy of Continuous Professional Education, Healthcare Ministry of Russian Federation

8. Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation

Abstract

Community-acquired pneumonia is one of the most common acute infectious diseases that has a significant share in the structure of mortality from respiratory diseases. It is extremely important to select rational antibiotic therapy which ensures optimal clinical efficacy, improved outcome, reduced rate of antibiotic resistance selection, and minimization of side effects.Methods. The target audience of these clinical recommendations are therapists, general practitioners, pulmonologists, anesthesiologist-resuscitators, and clinical pharmacologists. Each thesis-recommendation about diagnostic and therapeutic procedures has been scored according to the scale of classes of recommendations from 1 to 5 and A, B, C scale of the levels of evidence. The clinical recommendations also contain comments and explanations to these theses, algorithms for the diagnosis and treatment, and reference materials on the use of antibacterial drugs and microbiological (culture) tests.Conclusion. The presented clinical guidelines cover current information about the etiology, clinical manifestations, diagnosis and treatment tactics for community-acquired pneumonia. The presented clinical guidelines have been approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation in 2021. 

Publisher

Scientific and Practical Reviewed Journal Pulmonology

Subject

Pulmonary and Respiratory Medicine

Reference271 articles.

1. Chuchalin A.G., Sinopal’nikov A.I., Kozlov R.S. et al. [Community-acquired pneumonia in adults: practical guidelines for diagnosis, necessity, and prevention: a guide for physicians]. Klinicheskaya mikrobiologiya i antimikrobnaya khimioterapiya. 2010; 12 (3): 186–225. Available at: https://cmac-journal.ru/publication/2010/3/cmac-2010-t12-n3-p186/cmac-2010-t12-n3-p186.pdf (in Russian).

2. Rachina S.A., Sinopal’nikov A.I. [Infectious diseases of the lower respiratory tract]. In: Moiseeva V.S., Kobalava Zh.D., Maeva I.V. et al. (eds). [Fundamentals of Internal Medicine]. Moscow: MIA; 2020. Vol. 1: 145–205 (in Russian).

3. American Thoracic Society; Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am. J. Respir. Crit. Care Med. 2005; 171 (4): 388–416. DOI: 10.1164/rccm.200405-644ST.

4. Chalmers J.D., Rother C., Salih W., Ewig S. Healthcare-associated pneumonia does not accurately identify potentially resistant pathogens: a systematic review and meta-analysis. Clin. Infect. Dis. 2014; 58 (3): 330–339. DOI: 10.1093/cid/cit734.

5. Gross A.E.,Van Schooneveld T.C., Olsen K.M. et al. Epidemiology and predictors of multidrug-resistant community-acquired and health care-associated pneumonia. Antimicrob. Agents Chemother. 2014; 58 (9): 5262–5268. DOI: 10.1128/AAC.02582-14.

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