Federal clinical guidelines on diagnosis and treatment of idiopathic pulmonary fibrosis

Author:

Avdeev S. N.1ORCID,Aisanov Z. R.2ORCID,Belevskiy A. S.2ORCID,Ilkovich M. M.3ORCID,Kogan E. A.4,Merzhoeva Z. M.4ORCID,Petrov D. V.5,Samsonova M. V.6ORCID,Terpigorev S. A.7,Trushenko N. V.1ORCID,Trofimenko I. N.8ORCID,Tyurin I. E.9ORCID,Chernyaev A. L.10ORCID,Chernyak B. A.11ORCID,Chernyak A. V.6ORCID,Chikina S. Yu.4ORCID,Chuchalin A. G.2ORCID,Shmelev E. I.12ORCID

Affiliation:

1. Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University); Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia

2. Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation

3. Federal State Budgetary Educational Institution of Higher Education “Academician I.P. Pavlov First St. Petersburg State Medical University” of the Ministry of Healthcare of Russian Federation

4. Federal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

5. Budgetary Healthcare Institution, Omsk region “City Clinical Hospital No.1 named after Kabanov A.N.”

6. Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia

7. M.F.Vladimirskiy State Moscow Regional Research Clinical Institute

8. Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuing Professional Education”, Healthcare Ministry of the Russian Federation

9. Russian Federal Academy of Continued Medical Education, Healthcare Ministry of Russia

10. Federal Pulmonology Research Institute, Federal Medical and Biological Agency of Russia; Pirogov Russian National Research Medical University (Pirogov Medical University), Ministry of Health of the Russian Federation; Avtsyn Research Institute оf Human Morphology оf Federal State Budgetary Scientific Institution “Petrovsky National Research Centre оf Surgery”

11. Irkutsk State Medical Academy of Postgraduate Education – Branch Campus of Irkutsk State Medical Academy of Postgraduate Training

12. Federal Central Research Institute of Tuberculosis

Abstract

Idiopathic pulmonary fibrosis (IPF) is a specific form of chronic fibrotic interstitial pneumonia with a progressive course and poor prognosis. The prevalence of IPF in the Russian Federation is about 8 – 12 cases per 100,000 population. The basic treatment of IPF is antifibrotic agents.Methodology. The target audience of these clinical recommendations are therapists, general practitioners, pulmonologists, pathologists, radiologists, and medical rehabilitation doctors. Each thesis-recommendation about diagnostic and therapeutic procedures has been scored according to the scale of classes of recommendations from 1 to 5 and A, B, C scale of the levels of evidence. Clinical recommendations also contain comments and explanations to the theses, algorithms for the diagnosis and treatment of idiopathic pulmonary fibrosis, and reference materials.Conclusion. The presented clinical guidelines cover current information about the etiology and pathogenesis, clinical manifestations, diagnosis, treatment, and prevention of idiopathic pulmonary fibrosis. These guidelines were approved by the Scientific and Practical Council of the Ministry of Health of the Russian Federation in 2021. 

Publisher

Scientific and Practical Reviewed Journal Pulmonology

Subject

Pulmonary and Respiratory Medicine

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