Mechanisms of Presbylarynx and Current Management

Abstract

Presbylarynx is a condition characterized by age-related changes in the laryngeal structures that result in altered voice quality and function. This review explores the pathological mechanisms, clinical symptoms, and treatment options for presbylarynx. Pathologically, presbylarynx involves structural changes in the vocal folds, including muscle atrophy, thinning of the vocal fold mucosa, and alterations in connective tissue, which collectively contribute to decreased vocal fold elasticity and closure. Clinically, individuals with presbylarynx often experience a weakened voice, hoarseness, vocal fatigue, and reduced voice stability. These symptoms are compounded by changes in respiratory function and neurological control of the vocal folds. Treatment strategies for presbylarynx include voice therapy to strengthen vocal fold muscles and improve voice quality, pharmacological interventions such as anti-inflammatory medications and steroids to manage inflammation, and surgical approaches like vocal fold augmentation to restore vocal fold function. Emerging technologies such as neural-machine interfaces offer potential for future advancements in treating this condition. This review highlights the need for comprehensive management approaches to improve the quality of life for individuals affected by presbylarynx.