The Use of Raman Spectroscopy to Assess the Degradation of Poly(p-dioxanone) Fibre Intended for Medical Purposes

Author:

Jezbera DanielORCID,Loskot JanORCID,Nalezinková MartinaORCID,Myslivcová Fučíková AlenaORCID,Bezrouk AlešORCID

Abstract

Raman spectroscopy can be used in chemistry not just to determine chemical composition, but also to obtain further information on the material structure. In the spectra of semi-crystalline polymers, distinct bands characteristic of the crystalline or the amorphous phase can be found, the degree of crystallinity determined from them, and the degree of polymer degradation estimated from the crystallinity. In the present study, changes in the 1733 cm−1 band shoulder in Raman spectra of poly(p-di­oxanone) fibres subjected to hydrolytic degradation were evaluated. For different degradation periods, the areas under the shoulder of this band were calculated and a model deconvolution of this band into assumed crystalline and amorphous peaks was also performed. The areas under the shoulder, as well as the model peaks' parameters, were compared with the crystallinity values obtained by differential scanning calorimetry, achieving a good agreement. This work shows an example of using Raman spectroscopy when studying the hydrolytic degradation of polymers.

Publisher

Czech Chemical Society

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