Multicomponent synthesis of functionalized 2-amino-4<i>H</i>-pyrans initiated by the Knoevenagel reaction-Reference-Cited by-同舟云学术

Multicomponent synthesis of functionalized 2-amino-4<i>H</i>-pyrans initiated by the Knoevenagel reaction

Published:2023-02-15 Issue:2 Volume:59 Page:197-210
ISSN:0514-7492
Container-title:Журнал органической химии
language:
Short-container-title:Žurnal organičeskoj himii

Author:

Dyachenko I. V¹,Dyachenko V. D¹,Dorovatovskii P. V²,Khrustalev V. N³⁴,Nenajdenko V. G⁵

Affiliation:

1. Lugansk State Pedagogical University

2. National Research Center “Kurchatov Institute”

3. Peoples’ Friendship University of Russia (RUDN University)

4. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences

5. Lomonosov Moscow State University

Abstract

The multicomponent condensation of aldehydes, malononitrile derivatives, 1,3-dicarbonyl compounds of the carbo- and heterocyclic series, and alkyl halides has been studied. The transformation is initiated by the Knoevenagel reaction and leads to the formation of functionally substituted condensed 2-amino- 4 H-pyrans. The structure of a number of products was studied by X-ray diffraction.

Publisher

The Russian Academy of Sciences

Reference42 articles.

1. Synthesis and Pharmacological Activities of Pyrano[2,3-d]pyrimidine and Pyrano[2,3-d]pyrimidine-5-one Derivatives as New Fused Heterocyclic Systems

2. El-Shwiniy W.H., Shehab W.S., Zordok W.A. J. Mol. Struct. 2020, 1199, 126993

3. Drewe J.A., Xiong C.S., Wang Y. Пат. 6906203 (2005). США. РЖХим. 2006. 06.14-19О.57П.

4. Шевердов В.П., Андреев А.Ю., Насакин О.Е., Гейн В.Л. Хим.-фарм. ж. 2014, 48, 25-28.

5. Construction and functionalization of pyranone ring fused with pyran moiety: Design and synthesis of novel pyrano[4,3-b]pyran-5(4H)-ones as potential inhibitors of sirtuins

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