Affiliation:
1. Ufa Institute of Chemistry, Ufa Federal Researcher Centre of the Russian Academy of Sciences
Abstract
Heterocyclization of 3-[(alkylsulfanyl)methyl]pentane-2,4-diones with isonicotinic acid hydrazide in ethanol in the presence of catalytic amounts of hydrochloric acid without or under microwave activation leads to new 4-({4-[(alkylsulfanyl)methyl]-3,5-dimethyl-1 H -pyrazole-1-yl}carbonyl)pyridines. Under analogous conditions, 3-[(alkylsulfanyl)methyl]pentane-2,4-diones are converted to the corresponding 4-[(alkylsulfanyl)methyl]-3,5-dimethyl-1 H -pyrazoles.
Publisher
The Russian Academy of Sciences