Affiliation:
1. Institute of Organic Chemistry, Scientific Technological Centre of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
2. Molecule Structure Research Center NAS RA
Abstract
An available method for the synthesis of 2-diphenylphosphoryl- N -substituted aziridines with high yields has been developed by the interaction of (1,2-dibromoethyl)(diphenyl)phosphine oxide with a number of primary amines, in particular, methyl-, ethyl-, isopropyl-, tert -butyl-, cyclohexyl- and benzylamines at room temperature in the presence of sodium hydroxide. The antibacterial activity of obtained compounds was studied.
Publisher
The Russian Academy of Sciences