Affiliation:
1. Papanin Institute for Biology of Inland Waters
Abstract
The inhibitory ability towards proteases was studied in the extracts of plerocercoids from the liver of perch (Perca fluviatilis Linnaeus), as well as in the excretory-secretory products and extracts of mature and immature cestodes Triaenophorus nodulosus (Pallas, 1781) from the intestine of pike (Esox lucius Linnaeus). It was found that excretory-secretory products and extracts of both mature and immature T. nodulosus display varying degrees of inhibitory ability against proteases. A significant decrease in activity was noted under the action of the studied samples on the activity of commercial trypsin. Tapeworm extracts exhibit a greater inhibitory ability compared to excretory-secretory products. At the same time, the extract of immature worms inhibits the activity of proteases more strongly than that of mature ones. The inhibitory ability is more closely associated with the extract of worms lacking the brush border than with the tegumental brush border fraction.
Publisher
The Russian Academy of Sciences