Synthesis and biological activity of 4-aryl-2-hydroxy-4-oxo-<i>N</i>-(2-sulfamoylphenyl)but-2-enamides-Reference-Cited by-同舟云学术

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Synthesis and biological activity of 4-aryl-2-hydroxy-4-oxo-<i>N</i>-(2-sulfamoylphenyl)but-2-enamides

Published:2023-05-15 Issue:5 Volume:93 Page:664-669
ISSN:0044-460X
Container-title:Журнал общей химии
language:
Short-container-title:Žurnal obŝej himii

Author:

Gein V. L¹,Nazarets O. V¹,Romanova A. V¹,Bobrovskaya O. V¹,Novikova V. V¹,Makhmudov R. R²³,Balyukina L. A²

Affiliation:

1. Perm State Pharmaceutical Academy

2. Perm State National Research University

3. Federal Research Center for Medical and Preventive Health Risk Management Technologies

Abstract

The reaction of methyl esters of 4-aryl-2-hydroxy-4-oxobut-2-enoic (aroylpyruvic) acids with 2-aminobenzenesulfonamide in glacial acetic acid in the presence of anhydrous sodium acetate, 4-aryl-2-hydroxy-4-oxo N -(2-sulfamoylphenyl)but-2-enamides were obtained. The analgesic and antimicrobial activity of the obtained compounds was studied.

Publisher

The Russian Academy of Sciences

Reference11 articles.

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2. Москалик М.Ю. Автореф. дис. … докт. хим. наук. Иркутск, 2021. 42 с.

3. Гейн B.Л., Бобровская О.В., Дмитриев М.В., Махмудов Р.Р., Белоногова В.Д. // ЖОХ. 2018.Т. 88. Вып. 6. С. 914

4. Synthesis and Biological Activity of Compounds Obtained by Reacting Methyl Aroylpyruvates with Sulfadimidine

5. Гейн В.Л., Бобровская О.В., Гейн Л.Ф. // ЖОрХ. 2014. Т. 50. Вып. 11. С. 1703

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