Synthesis of diethyl 6-amino-1,4-diaryl-2-oxo1,2,3,4-tetrahydropyridin-3,5-dicarboxylates based on the reaction of arylmethylidenecyanoacetic esters with <i>N</i>-arylamido esters of malonic acid-Reference-Cited by-同舟云学术

Synthesis of diethyl 6-amino-1,4-diaryl-2-oxo1,2,3,4-tetrahydropyridin-3,5-dicarboxylates based on the reaction of arylmethylidenecyanoacetic esters with <i>N</i>-arylamido esters of malonic acid

Published:2023-04-15 Issue:4 Volume:93 Page:516-524
ISSN:0044-460X
Container-title:Журнал общей химии
language:
Short-container-title:Žurnal obŝej himii

Author:

Avagyan K. A¹,Sargsyan M. S¹,Badasyan A. E¹,Sargsyan A. A¹,Manukyan A. G¹,Panosyan G. A¹,Ayvazyan A. G¹,Khachatryan A. Kh.¹²

Affiliation:

1. Scientific Technological Center of Organic and Pharmaceutical Chemistry of the National Academy of Sciences of the Republic of Armenia

2. Crisis Management State Academy

Abstract

The reaction of arylmethylidenecyanoacetic esters with N -arylamides of malonic acid led to the formation of previously unknown diethyl 6-amino-1,4-diaryl-2-oxo-1,2,3,4-tetrahydropyridine-3,5-dicarboxylates in 15-83% yields. Antibacterial activity of some obtained compounds was studied.

Publisher

The Russian Academy of Sciences

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