Synthesis of (2 E )-5-arylpent-2-ene-4-ynoates

Abstract

An effective method was developed for the synthesis of (2 E )-5-arylpent-2-ene-4-ynoates based on the olefination-dehydrobromination of (2 Z )-2-bromo-3-arylprop-2-enals obtained by bromination of commercially available cinnamaldehyde and its derivatives.